Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Or, this year, to be women with a story to tell about abuse, sexual or otherwise — a couple of whom shared #MeToo moments in our pages. Carlotta Gall told the story of Henda Ayari, a French citizen of North African heritage and anti-Salafist activist who accused a prominent Oxford professor of raping her.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
根据荷兰经济政策研究局(Netherlands Bureau for Economic Policy Analysis)发布的《世界贸易监测》(World Trade Monitor)报告，以美元计算，去年跨越国际边境的商品总价值下降了13.8%，是自2009年以来的首次萎缩。这一暴跌很大程度上源于中国和其他新兴经济体的放缓。
The dumbest 'smart' objects of 2016
Trends and targets in antiviral phototherapy
While you're studying, pay attention to the material you know will be on a test and write a quick practice question. Start a new document on your laptop and add questions as you think of them.
此次涵盖95个项目（去年为90个）的排行榜中，来自7个国家的9所院校为首次进入榜单。排名第41位的法兰克福金融管理学院(Frankfurt School of Finance & Management)是今年排名最高的新入榜者。这家德国学院拥有性别比例最平衡的项目之一，女性占学员总数的49%。
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Brazil's President Dilma Rousseff, who is facing impeachment, slashed her own salary by 10% to $103,400 a year last October as part of a wider austerity drive.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The magazine put his net worth at $3.5 billion, down $1 billion from the rankings it issued a year ago.
I expect more companies to develop leaders who know how to manage networks — not just the traditional internal network of employees, but more loosely connected webs of suppliers and contractors, managed remotely via the internet and social media.
ACE2 as a potential therapeutic target for pandemic COVID-19
About 40 per cent of entrepreneurs derive most of their income from their company with an average salary of about $194,000 compared to $171,000 for non-entrepreneurs. Entrepreneurs in Asia/Oceania seem to be the most successful. Nearly half (48 per cent) of them earn most of their income from their company and earn the highest salary ($251,000 on average), just ahead of those based in the Middle-East ($244,000).
“An interviewer walked inta closet instead of the meeting room.”
Diagnostic technologies for COVID-19: a review
Mr Cook’s decision to expand its cash return programme of dividends and share buybacks helped to defuse the situation with the activists, returning $94bn to date. In the end, he stared down the challenge just long enough for the next wave of iPhone growth to hit and new products to emerge from Sir Jonathan Ive’s workshop.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
This was never more powerful than when he talked publicly for the first time about his sexuality.
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
8. Greenland sharks live for a very long time
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
在出售给Facebook前，WhatsApp一直特别反对植入广告。该公司首席执行官让o库姆在自己桌上一直贴着联合创始人布莱恩o阿克顿留下的一张便条，随时提醒自己牢记公司的核心价值观：“不要广告！不要游戏！不要宣传噱头！”这样一来，短信应用只好想出别的创意。比如Tango就在用户的短信“收件箱”里插入广告。中国互联网巨头腾讯公司旗下的短信应用——微信，则通过游戏、贴纸（类似于表情符号）和移动购物等方式谋取赚钱之道。Kik则提供一种被一些人称为“聊天广告”的功能，用户通过它能和幽默网站Funny or Die及电影信息网站Moviefone这类品牌运营的聊天程序进行交谈。
The Chinese-made 3D fantasy/adventure film "Monster Hunt" broke a string of box-office records on its release in the country in July 2015, becoming the highest grossing film of the year in the Chinese mainland.
在2017年FT对全球95个管理学硕士项目的排行中，虽然瑞士圣加仑大学(University of St Gallen)继续蝉联冠军，但法国和英国商学院分别以24个和18个项目入围成为中坚力量。超过一半的英国商学院排名上升，而只有一家法国商学院排名上升。三分之一的英国商学院排名上升5位，相比之下，三分之二的法国商学院排名下降5位或更多。
Influenza neuraminidase: A druggable target for natural products
Agents and investment institutions are now flooding the sector, causing additional changes to the platforms in the world's second-largest economy, the report said.
No matter whether you’re looking for big international events, delicious food, natural wonders or simply relaxation on a beach, these places should be on your checklist.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Recently, however, the buyback boom has started to fade. The Standard & Poor's 500 Buyback Index, which tracks the 100 companies with the largest share repurchase ratio, recently recorded its first quarterly decline since mid 2012. As stock prices reach record highs, the boost from share repurchases diminishes, making it more valuable for companies to invest in longer-term projects or use extra cash for acquisitions.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
China's online game revenue in 2008 was CNY20.8 billion, accounting for about 27% global share, ahead of South Korea at 21% and slightly behind the U.S. at 29%, according to an earlier report by Shanghai-based market research firm iResearch. The firm also predicted that China is likely to surpass the U.S. to become the world's largest by the end of 2009.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
In an industry enthralled to rehashed stories that strike a familiar chord with audiences, give Pixar credit for often trying something new and pushing their viewers into uncharted territories. Coco, directed by Toy Story 3’s Lee Unkrich, has a visual look based around Mexico’s Dia de los Muertos (Day of the Dead). It’s about a young boy named Miguel who idolises legendary guitar player Ernesto de la Cruz and wants to learn how to play as well as he could. So he goes on a transformative odyssey of self-discovery into the realm of the dead to find his long-deceased idol and learn some lessons about the nature of creativity and originality. Whether it can reach the heights of Pixar’s 2015 masterpiece Inside Out remains to be seen, but Coco should surely be a feast for the eyes. Released November 15 in France, November 22 in the US, Croatia and the Philippines, and November 30 in Israel. (Credit: Disney-Pixar)
Watching Under the Skin again brought to mind another comparison: Orson Welles – the Welles who succeeded in creating a hoax martian invasion on the radio and who, in F for Fake (1975), got his partner Oja Kodar to walk around the streets in a miniskirt, secretly filming the lascivious expressions of the non-actor guys looking at her.
May the joy and happiness around you today and always.
The strength of Kellogg/HKUST is the quality of its participants.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
6.Do All the Work, Plus More
The Internet has flattened the world, and Facebook has banded us together as one big family. Our grandfathers inherited regions, my generation inherited nations, you have inherited the world. You are now only 4.74 people away from any human being and an average of two days away from any inhabited corner of the world. So travel. Africa, Europe, India, China or Brazil, go where you can learn the most, embrace what can teach you the most.
Inhibition of SARS coronavirus helicase by bismuth complexes
The announcement comes from the British Fashion Council (BFC), who surveyed designers ahead of the shows and found none of the 80 designers in the September line-up would be using fur.
3. Your boss received your résumé from a contact of a contact。
The Belty is great that it uses technology to track fitness, water intake, and posture, but for $395, you might be better off getting the same in a stylish smart watch or activity tracker.
The theory describes Type B individuals as a contrast to those of Type A. Type B personality, by definition, are noted to live at lower stress levels. They typically work steadily, and may enjoy achievement, although they have a greater tendency to disregard physical or mental stress when they do not achieve.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
In August, the holdings were to the tune of $80.4 billion while it stood at $79.7 billion in July.
Today's and tomorrow's technology sits on top of multiple layers, every one of which is changing and has to inter-operate with others. This makes our gadgets, the internet of things, phones and laptops unstable. And it makes consumers irritated. How many of your apps actually work--and actually make life easier, faster or more fun? I'd expect to see consumer cynicism grow, as delight is overtaken by disappointment. This will put pressure on hardware and software developers to deliver that most boring of qualities: reliability.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Widely misunderstood as a biopic about the novelist David Foster Wallace, Mr. Ponsoldt’s film is a comedy of journalistic bad manners and a bitter, knowing satire of the machinery of literary fame. Jesse Eisenberg and Jason Segel use the conventions of the buddy movie to perfect a new subgenre: the frenemy film.
Sectors: out of favour
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Pink, LeBron James, Selena Gomez, Ian Somerhalder, Jay-Z and Beyonce, Ben Affleckalso made the list.
IDC believes that the rising disposable income of Chinese people has resulted in greater consumption, which contributed to the rapid growth of the domestic smartphone market.
Sorry, folks, but if you're an investor hoping America's political internecine wars will improve in the near future, just don't invest. The war between Congress with it's abysmal 10% approval rating and the president, the war between the Dems, GOP and the tea party, is going to get even worse, upsetting markets and the economy even more.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
It is the eighth straight year that the metropolis has led Chinese cities in terms of consumer spending.
She also said that in the longer-term the other “R” was “reset”, by which she explained that monetary and fiscal policies around the world still had a long way to go before they could be classed as normal. “The final reset is those structural reforms that are necessary in all corners of the world,” she added.
France, one of the most visited countries in the world, ranks No. 9 overall. It is No. 2 in Cultural Influence and No. 6 in Power.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
室内环境：这栋砖砌结构、灰泥粉饰并铺着瓷砖屋顶的两层楼房屋由Dorr & Dorr公司设计，于1916年完工，近15年内曾经翻修。该房屋采用了半牧场、半工匠艺术的设计风格，运用了简洁的线条、开敞式空间、典雅的木制品和彩色玻璃等设计。翻修工程由明尼阿波利斯市Sala建筑公司的约瑟夫·麦茨勒(Joseph Metzler)完成。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
New Year should be a time of banked-up fines, the scent of flowers and wine, good talk, good memories and loyalties renewed. But if all else is lacking - love will do.
A Datafolha polling group survey published in the Folha de S. Paulo newspaper showed that at Saturday's Brazil versus Chile match, 67 percent of attendees classified themselves as white and 90 percent came from Brazil's top two economic classes, which represent about 15 percent of the country's population.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Porto is nearly synonymous to port wine, and also its rich history. The city's historic center and the Alto Douro Wine Region have been listed as UNESCO World Heritage Sites.
Kristen Stewart definitely did some 'butt' kicking at the Nickelodeon Kids' Choice Awards 2013 on Saturday. The star strutted down the purple carpet in a dazzlingly deep blue and black top and tiny shorts that had a miniscule checkerboard pattern. Kristen was nominated for two awards at the live show - Favorite Movie Actress for The Twilight Saga: Breaking Dawn - Part 2 and Favorite Female Buttkicker for Snow White and the Huntsman.
It was the fastest growth rate among the top 10 countries on the EPO's patent-filing league table.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Better still was Iain Roberts, global managing director of the design company Ideo, who asked a question to which I hope never to hear the answer: “How to activate insights around latent mobility or multimodal needs?”
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
“The key thing about Friends is that it’s about people working out how they are going to live their lives — what kind of relationships are they going to have, what kind of job, and the difficulties of settling down,” says Mills to the Daily Mail. “You’re engaged in all those questions about escaping from your family, becoming an adult and working out what you want to be.”And that’s one of the key issues in the youth culture of the 1990s.
Data released by the UK National Health Service last year on patient admissions revealed an alarming rise in various nutritional and communicable diseases in the past decade.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
While at least four engines tend to repeat from one year’s 10 best list to the next, only two of last year’s powerplants remain recognized for 2014, the Honda Accord’s peppy and fuel-efficient 3.5-liter V6 and the powerful supercharged 3.0-liter V6 featured in the Audi S5.
The EU’s Americas gambits
A modular microarray imaging system for highly specific COVID-19 antibody testing
Jiang Yiyi at the China Tourism Academy suggests China adopt a long-term national plan to improve the country's image and investment in inbound tourism to attract more visitors.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
I have never ordered an ice bucket for my red wine. In fact, come to think of it, I have never ordered an ice bucket for white wine, Champagne or dessert wine.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Mr Li said the economy’s strength came as a result of the government shunning strong stimulus policies and its push for supply-side reforms.
The Disaster Artist is part buddy movie, part show-business fable, and part behind-the-scenes DVD featurette.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
在苹果今年6月举行的全球开发者大会(Worldwide Developer Conference)上，库克被应用开发者团团围住，要求与他自拍合影。到了10月的iPad发布会，他甚至自己讲起了笑话。他还是一贯的着装，简单朴实：黑衬衫，牛仔裤，衬衫下摆散着。他说，Apple Watch得到了“深谙时尚与风格——比我还懂的人”的热烈好评，一边说，一边心照不宣地指着轻声发笑的观众。
Making Airbnb go away might not be so easy. A recent Quinnipiac poll found that 56 percent of the responders thought New Yorkers should be allowed to rent rooms out to strangers. “We don’t want to turn into hotels, but at the same time people want to rent out their apartments sometimes,” said Paul R. Gottsegen, the president of Halstead Management Company, which manages 250 residential properties in the city.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Lopez Short is the name of the game, judging from the red carpet looks of Beyoncé and Jennifer Lopez. Both divas went for thigh-high dresses to show off their gams4, with strategically cut out neck and shoulder detail, but where Beyoncé opted to stand out in fire engine red, J. Lo went for soft and satiny earth tones.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The statement said: "We sincerely apologize to Moonlight, La La Land, Warren Beatty, Faye Dunaway, and Oscar viewers for the error that was made during the award announcement for Best Picture."
1.take hard classes
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Lenovo CEO Yang Yuanqing
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
James Bond Themes 3. "Skyfall" by Adele
“I thought teaching wasn’t a proper career option. My teacher said I’d need to have a high boredom threshold if I wanted to become a teacher,” he recalls.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Foreign investment in emerging markets has dropped to the lowest level since the financial crisis as investors are braced for the fallout of the first US interest rate rise in nearly a decade.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
According to the financial data provider Wind Information Co Ltd, listed companies in China's A-share market earned 2.47 trillion yuan in profits last year. Of those listed companies, 2000 plan to pay out 700 billion yuan to their shareholders.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
In truth, slower growth of about 8 per cent could be better for China and for the world. More environmentally sustainable and equitable outcomes would ease popular concerns and higher consumption would ease tensions over global trade.
Anti-HIV drug repurposing against SARS-CoV-2
Hartz started Eventbrite, an online ticketing platform, with her now-husband Kevin in 2006. Since its founding, the company has raised $140 million from firms like Sequoia Capital and Tiger Global Management and reached $2 billion in gross ticket sales this September. Entrepreneurship forced Hartz to appreciate candid and collaborative conversations. "I had to learn how to ask for help," she says. "Everyone always thinks it's brave to go out alone, but I think it's even braver to put yourself out there in front of others, and to figure out how to work together."
"There are 1,400 individuals who are involved in the departures for jihad,for terrorism, in Syria and in Iraq," Valls told BFMTV.
Length-scale dependence of protein hydration-shell density
For now, occasional high-ticket deals such as the Dah Sing Financial Centre and the purchase of a HK$2.1bn luxury house on the affluent Peak, come amid wider pessimism about the sector. The office sector showed the most activity in the first quarter this year, but this still translated into only eight deals in total, according to CBRE.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
It seems safe to predict lots more noise and very little progress for the rest of 2017. And that will continue to be a damaging combination for business and the UK economy.
You've usually stated in pastinterviews that you have connections to your characters. In Aldnoah Zero, whichis currently airing, what do you think is your connection to Inaho?
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The federal control board has requested a revised fiscal plan that has to be approved by end of January, saying that the one Garcia submitted last year was in part unrealistic and relied too heavily on federal funds. Garcia had refused to submit a revised plan to include austerity measures. Rossello has said he would request an extension of that deadline as well as an extension of a moratorium that expires in February and currently protects Puerto Rico from lawsuits filed by angered creditors.
这是今年最精致的浪漫电影与最尖锐的反浪漫电影，均来自美国电影界最缜密的聪明人。两部影片之间的关系最好用一首威廉·布莱克(William Blake)的诗歌来总结——《土块与卵石》(The Clod and the Pebble)。
About this collection
Fund shareholders weren’t wasting any time reacting to this year of disappointment. Collectively, they’ve added just $35 billion to active stock-picking funds in the last 11 months, less than a quarter of the $162 billion they added in 2013, which was the first year of positive flows for the industry since 2007. This is not to say that they were sitting still. ETFs and passive index funds took in over $206 billion in net deposits through Thanksgiving, and Vanguard surpassed the $3 trillion mark sometime in late summer. Investors seem to have decided that they’d rather bet on the horses than the jockeys, after all.