Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The show’s sense of humor remains keen without relying on nudity, swearing and sexting. This gives the show a refreshing aura in an age where shows are constantly trying to push the envelope in terms of racy content.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Denmark, Norway, Switzerland, the Netherlands and Sweden are the world's happiest countries, according to the survey of 156 countries. Rwanda, Burundi, the Central African Republic, Benin and Togo -- all nations in Sub-Saharan Africa -- are the least satisfied with their lives, the report said. China ranks 93rd in the list.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Consoles: Xbox One, Xbox 360
Trends and targets in antiviral phototherapy
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
赞助Summly的有香港亿万富翁李嘉诚的风投部门Horizons Ventures，以及演员艾什顿库彻(Ashton Kutcher)和斯蒂芬弗莱(Stephen Fry)、Spotify的沙基尔汗(Shakil Khan)和Zynga的马克平卡斯(Mark Pincus)等技术与媒体界名人。
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
BuzzFeed News defined “fake news” as news that was verifiably “100 percent false” and drawn from a list of 96 websites purposely created to disseminate false information.
圣保罗报的民意调查是基于在贝洛奥里藏特（Belo Horizonte）的米内朗球场（ Mineirao）对693名球迷进行的采访，统计误差为4%左右。
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Chicago-based rival AT Kearney is also preparing for a change at the top, with a vote to replace Johan Aurik, who has already served the maximum two terms as managing partner, due to take place in the first quarter of 2018. His replacement will be expected to focus on how to pull AT Kearney out of the ranks of mid-sized players.
In this emotional comedic drama, a selfish car dealer named Charlie Babbitt learns that he has a brother after his estranged father dies. He is upset to learn that said brother, Raymond, received his father's $3 million estate despite living with severe autism that has left him in a mental institution. Charlie learns that Raymond is a savant with outstanding capabilities for mental math and takes advantage of this skill by using Raymond to count cards in Vegas.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
What? Hasn't his firm made enough money off Bernanke's cheap money printing? So he's blaming 'lower growth on fiscal austerity, ' even as Bernanke keeps blowing up the Fed's balance-sheet bubble by trillions under the delusion he's America's savior because our dysfunctional Congress failed?
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Besides exploring the overall ranking, prospective international students can narrow their search by browsing regional and country rankings. These rankings were determined solely by how schools performed in the overall list.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Captain America: Civil War will hit theatres May 6, 2016. Who's side are you on?
Antiviral drug discovery: broad-spectrum drugs from nature
In the post-experience ranking, alumni from London Business School enjoyed the highest salaries on average three years after graduation at around $130,000 and the highest score for aims achieved (87 per cent). The programme was also ranked first for placement success and for international course experience. Its alumni were also ranked second for international mobility and career progress.
Influenza neuraminidase: A druggable target for natural products
Only three Hollywood productions, 'Furious 7', 'Avengers: Age of Ultron', and 'Jurassic World', made it into the top 10 at the Chinese box office in 2015.
The research also suggests there maybe a value in finding a job through an internship. Interns who accepted a job offer had higher salaries than those who had received an offer but refused it. Those interns who did not receive an offer had lower salaries still. The gap between these groups had increased three years after graduation.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Ah yes, the other reason Sacramento shouldn't tank: Philadelphia has the option to swap picks with them this year. It's actually impossible for the Kings to get the No. 1 pick because of that, and it hurts their chances at a top-three pick overall.
The role of biosensors in the detection of emerging infectious diseases
Despite being the most heavily nominated stars of the evening, Taylor - who did not attend the event - was overshadowed by 19-year-old singer Shawn who cleaned up at the awards show.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
James Bond is one of the few constants that movie lovers have in this crazy world of ours. We seem to know that, no matter what, a new Bond movie is always on the way.
Theresa May is still facing resistance from within her own party. Vince Cable, the Liberal Democrats’ sage and leader, still thinks Brexit may not really happen.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
transport（n /v 运输；狂喜），trans转移，port搬运
Inhibition of SARS coronavirus helicase by bismuth complexes
Hanging on the coat tails of Ronaldo and Messi are NBA star LeBron James (pound 53 million) and tennis player Roger Federer (pound 46 million).
In the past five years, China's exports of goods grew at an annual average of 6.5 percent, with its share in the global market rising form 10.4 percent in 2010 to about 13.2 percent in 2015, faring much better than major global economies. Service trade grew over 13.6 percent each year, marking the world's second largest service trader.
4. Slacking at school
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
An investigation is continuing into how La La Land was wrongly named Best Picture rather than the triumphant Moonlight.
Agents and investment institutions are now flooding the sector, causing additional changes to content and platforms in the world's second-largest economy, the report said. A number of Internet gurus, including Lei Jun, investor and founder of tech firm Xiaomi, Zhou Hongyi, CEO of Qihoo 360 Technology, and China's richest man Wang Jianlin have all directly supported live video-streaming websites, a strong indication of the growing interest from capital investment.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
8.Your Boss Sucks
Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
Will a nation other than Brazil, Germany or Spain win the World Cup
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
I give you endless brand-new good wishes. Please accept them as a new remembrance of our lasting friendship.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Although she has already reached astonishing levels of success for her age, Maddie only gives herself a nine out of ten in terms of her career achievements.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Inflation (and deflation) won't rear its ugly head Surging oil production — along with slower global growth — has caused the price of petroleum to collapse from more than $100 a barrel last summer to barely $50 a barrel at the end of 2014. The effect has been to reverse an uptick in U.S. inflation earlier in the year.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The fundamentals of the Chinese economy remain sound, the capital adequacy ratio and provision coverage of commercial bans remain high, and we have many financial tools and instruments that can be used. We have the confidence, the ability, and the means to forestall systemic risks.
The survey of 11,500 workers by Chinese employment agency Zhaopin found that 50.9 per cent did not get an annual bonus at the end of 2016. Another 9.6 per cent were told their bonus had been delayed until after the new year holiday.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Salary three years after graduation and salary increase are the main criteria, each accounting for 20 per cent of the ranking’s weight. Most schools in the top 25 score well on at least one of these criteria. The top 10 schools would mostly also rank in the first 10 if salaries and their increases were excluded. The only exceptions are Nanyang Business School and China Europe International Business School, both underperforming in the doctoral and research ranks.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
This umbrella protects your dogs from the sun and rain.
The number of university graduates reached 7.65 million in 2016, hitting a new historic high, the Beijing News reported. Plus, the number of students graduating from secondary vocational schools hit 4.35 million, bringing the total figure to 12 million.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Let’s now travel to Greece. There, Andreas Georgiou, the head of its statistical agency between 2010 and 2015, faces prosecutions for his part in uncovering fake Greek public finance data for 2009 and setting the record straight. This week 40 groups, led by the American Statistical Association, and 651 individuals signed a statement in support of Mr Georgiou.
In this Jan. 24, 1984, file photo, Steve Jobs, chairman of the board of Apple Computer, leans on the new "Macintosh" personal computer following a shareholder's meeting in Cupertino, Calif
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Researchers at Google discovered that security questions as a standalone method for recovering access to accounts is not an efficient model.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The University of St Gallen’s domination of the Financial Times’ ranking of masters in management courses continues for another year.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Klay Thompson added 19 points and Andrew Bogut scored 13 for the Warriors, off to the best start by an NBA team since Dallas won its first 14 games in 2002-03. Golden State needs three wins to equal the league record of 15-0, held by the 1948-49 Washington Capitols and 1993-94 Houston Rockets.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Does he have the ability to communicate his plans for what comes next—whatever they might be—to a fan base that's rightfully demanding answers after another ugly season on and off the court?
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
7. “飞翔莲花”(Flying Lotus)，《你死了》(You’re Dead)， Warp。新融合乐绝不会对旧融合乐说抱歉，这只是升级而已。身为制作人的“飞翔莲花”既注重延续性，也注重破坏、模糊之美与跳跃剪辑的喧闹。他对死亡的组曲式沉思为不虔敬的智慧留出空间，《永远不能抓住我》(Never Catch Me)这首歌的歌词由肯德里克·拉玛(Kendrick Lamar)创作，堪称年度最佳。
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
When researchers at the University of Illinois set out to create a device that identifies chemicals by their scent, they didn't settle for the sensitivity of the human nose. Instead, they created an artificial nose that uses the smell of bacteria to identify and diagnose specific diseases.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
According to a notice jointly issued by the Ministry of Human Resources and Social Security and the Ministry of Finance, the average monthly payments for both enterprise and institution retirees will be increased by about 5.5% from the 2016 level.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.
A facile assay for rapid detection of COVID-19 antibodies
虽然唐尼主演的几部电影将在明年上映，但规模成本要比他的超级英雄电影小得多。直到2015年《复仇者联盟：奥创纪元》（Avengers: Age of Ultron）上映，他才能迎来下一个丰收季。
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
As it happened, the lenders to Seppenwolde never lost a guilder. Within weeks, they had liquidated all the East India shares and had recovered the money they had loaned.
“Someone resigned via a video conference call.”
Many successful entrepreneurs started later in life. J. K. Rowling (Harry Potter author), Julia Child (chef), and Sam Walton (Wal-Mart) all started their wildly successful brands after they were comfortably along in their lives. Having the experience that comes with age can give you a unique outlook on your business. Life experiences bring depth that the most educated young adult, by his or her nature, is less able to foresee.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
You can browse the full list at AskMen.com. Here are the top 10 women:
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
门萨智商测试的参试者必须是超过十岁半的儿童，测试包括两部分独立的行业标准评估。一部分主要测试语言推理能力;而另一部分包含表格和图形，测试视觉和空间逻辑能力。而来自坦姆赛德的妮诗在第一部分卡特尔III B测试中得到了最高的162分，在第二部分的文化能力量表(Culture Fare Scale)中得到了142分，该测试结果使她名列英国智商最高的前1%人群，而门萨测试成绩前2%的参试者都可以成为门萨会员。
纽约人向专栏提出的问题，不仅取决于他们的个人情况，还取决于当今的重大问题，比如住房成本上升、士绅化、豆腐渣工程。最终，2014年成为了一个一切都在增长的年份，增长的包括房价、租金，以及最重要的——楼盘数量。根据纽约房地产委员会(Real Estate Board of New York)的数据，10月批准建设的单元达到了16700套。
Of course, the recovery of the job market has been, and probably will remain, incremental. Job growth needs to be much stronger to actually make a big dent in unemployment, which remains high at 7.9%, though down from 10% three years ago.[qh]
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Cross talk “Do Not Blame Me” (Cao Yunjin and Liu Yuntian)
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
200911/88512.shtmlA 1936 Nobel Peace Prize discovered at a South American pawn shop has been sold at auction in Baltimore for $1.16 million.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
This includes McKinsey, the consultancy that kick-started its secretive leadership election process in October with a gathering of more than 500 senior partners at the Grosvenor House Hotel in London. The next stage involves the firm’s 550 senior partners voting on a shortlist of candidates to replace Dominic Barton — the incumbent since 2009 — in January, followed by a run-off between the two most popular candidates in February.
Anti-HIV drug repurposing against SARS-CoV-2
在《醉乡民谣》(Inside Llewyn Davis)中，编剧兼导演乔尔?科恩(Joel Coen)和伊桑?科恩(Ethan Coen)兄弟俩挥之不去的忧伤情绪转化成了令人难忘的戏剧性场面。我觉得我的评论本应澄清，这部关于流行文化牺牲品的悲歌有一种特别的味道；其中一些部分相当阴郁。奥斯卡?伊萨克(Oscar Isaac)在片中出演一位自暴自弃的民谣乐手，宿命般地献身于他的艺术，他的卓越表演令这部影片极其震撼人心。
Length-scale dependence of protein hydration-shell density
Striking a balance may take a while, but working toward this list as a goal for starting your company will make the difference. How an owner feels about progress and how quickly a business can be up and running — and feeding that bottom line — will swiftly feel the impact.
6. Miranda Lambert “Platinum” (RCA Nashville) Ms. Lambert went from plucky upstart to glittery country royalty in next to no time, but with “Platinum,” her best album, she walks that line with breezy authority. By turns sentimental and profane, with an ideal ratio of gloss to grit, it’s a reminder of her irreducible strengths, and a dare to anyone who’d undervalue them.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Barack Obama went on the offensive over foreign policy in the third and final presidential debate, repeatedly accusing Mitt Romney of flip-flopping on major international issues but failing to deliver a killer blow to his opponent's resurgent campaign.
2. Worldwide Murders
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The private Facebook group chat that led to offers of admission being rescinded was named, at one point, "Harvard memes for horny bourgeois teens", the Crimson reported.
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"Quality supervision authorities at all levels must intensify quality supervision and keep cracking down on law violations to improve the quality of products and protect consumers' rights," said Mei Kebao, deputy head of the administration.